Andrew J. Flores

Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy

Joji Marie Teves, Vedanshi Bhargava, Konner R. Kirwan et al. · Frontiers in Neuroscience · 2018 · 69 citations · Full text

Mitophagy, Pathology, Redox Homeostasis +17

Preclinical evidence in support of repurposing sub-anesthetic ketamine as a treatment for L-DOPA-induced dyskinesia

Mitchell J. Bartlett, Andrew J. Flores, Tony Ye et al. · Experimental Neurology · 2020 · 36 citations · Full text

Neuromodulation Therapies, Pharmacotherapy, L-dopa-induced Dyskinesia +22

Ventral pallidum GABA and glutamate neurons drive approach and avoidance through distinct modulation of VTA cell types

Lauren Faget, Lucie Oriol, Wen-Chun Lee et al. · Nature Communications · 2024 · 30 citations · Full text

The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia

Andrew J. Flores, Mitchell J. Bartlett, Brandon Root et al. · Neuropharmacology · 2018 · 24 citations · Full text

Opioid Glycopeptide Mmp-2200, Functional Selectivity, Medicine +9

Excessive firing of dyskinesia-associated striatal direct pathway neurons is gated by dopamine and excitatory synaptic input

Michael Ryan, Allison E. Girasole, Andrew J. Flores et al. · Cell Reports · 2024 · 17 citations · Full text

Traped Dmsns, Synaptic Plasticity, Neurobiological Mechanism +15