Selective inhibition of BET bromodomains

P. Filippakopoulos, Jun Qi, S. Picaud, +22

Nature

Bet BromodomainsGeneticsPathogenesisMolecular GeneticsMedicine +1

Arginine methylation controls growth regulation by E2F‐1

Er-Chieh Cho, Shunsheng Zheng, Shonagh Munro, +12

The EMBO Journal

Structural analysis of human KDM5B guides histone demethylase inhibitor development

C. Johansson, Srikannathasan Velupillai, Anthony Tumber, +21

Nature Chemical Biology

Histone ModificationsChromatinChromatin StructureChromatin RemodelingNatural Sciences +11

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Anthony Tumber, Andrea Nuzzi, Edward S. Hookway, +25

Cell chemical biology

Arginine Methylation-Dependent Reader-Writer Interplay Governs Growth Control by E2F-1

Shunsheng Zheng, Jutta Moehlenbrink, Yi-Chien Lu, +11

Molecular Cell

Signal TransductionEpigenetic ChangeEpigenomicsMolecular BiologySystems Biology +2

Lysine methylation regulates the pRb tumour suppressor protein

Shonagh Munro, Nandkumar Khaire, Adam G. Inche, +2

Oncogene

Lysine MethylationMedicineEpigenetic ChangeEpigenomicsTumor Suppressor +4

Long non-coding RNA-derived peptides are immunogenic and drive a potent anti-tumour response

Wojciech Barczak, Simon M. Carr, Geng Liu, +9

Nature Communications

Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein

Simon M. Carr, Shonagh Munro, Benedikt M. Kessler, +2

The EMBO Journal

Developmental BiologySignal TransductionLysine MethylationCell RegulationCell Signaling +8

Citrullination-acetylation interplay guides E2F-1 activity during the inflammatory response

Fatemeh Ghari, Anne‐Marie Quirke, Shonagh Munro, +12

Science Advances

NEDDylation regulates E2F‐1‐dependent transcription

Sarah Jane Loftus, Geng Liu, Simon M. Carr, +2

EMBO Reports

Transcriptional RegulationMolecular RegulationGene RegulationGene ExpressionMedicine +4