α-Ketoamides as Broad-Spectrum Inhibitors of Coronavirus and Enterovirus Replication: Structure-Based Design, Synthesis, and Activity Assessment

Linlin Zhang, Daizong Lin, Yuri Kusov, +11

Journal of Medicinal Chemistry

Highly pathogenic coronavirus N protein aggravates lung injury by MASP-2-mediated complement over-activation

Ting Gao, Mingdong Hu, Xiaopeng Zhang, +32

Molecular basis for SH3 domain regulation of F-BAR–mediated membrane deformation

Yijian Rao, Qingjun Ma, Ardeschir Vahedi‐Faridi, +7

Proceedings of the National Academy of Sciences

Highly pathogenic coronavirus N protein aggravates inflammation by MASP-2-mediated lectin complement pathway overactivation

Ting Gao, Lin Zhu, Hainan Liu, +29

Signal Transduction and Targeted Therapy

The Nucleocapsid Protein of Severe Acute Respiratory Syndrome Coronavirus Inhibits Cell Cytokinesis and Proliferation by Interacting with Translation Elongation Factor 1α

Bing Zhou, Junli Liu, Qiuna Wang, +4

Journal of Virology

Acute Lung InjuryViral ReplicationF-actin BundlingViral PathogenesisImmunology +10

Diagnosis of Severe Acute Respiratory Syndrome (SARS) by Detection of SARS Coronavirus Nucleocapsid Antibodies in an Antigen-Capturing Enzyme-Linked Immunosorbent Assay

Yuling Shi, Yanping Yi, Ping Li, +4

Journal of Clinical Microbiology

Crystal structure of the papain-like protease of MERS coronavirus reveals unusual, potentially druggable active-site features

Jian Lei, J.R. Mesters, Christian Drosten, +3

Antiviral Research

Nonstructural Proteins 7 and 8 of Feline Coronavirus Form a 2:1 Heterotrimer That Exhibits Primer-Independent RNA Polymerase Activity

Yibei Xiao, Qingjun Ma, Tobias Restle, +5

Journal of Virology

Aluminacyclopropene:  Syntheses, Characterization, and Reactivity toward Terminal Alkynes

Hongping Zhu, Rainer Oswald, Hongjun Fan, +7

Journal of the American Chemical Society

Excess C2h2Terminal AlkynesMaterials ScienceEngineeringAlkene Metathesis +6

Synthesis and Structures of [{HC(CMeNAr)₂}Ge(S)X] (Ar = 2,6-<i>i</i>Pr₂C₆H₃, X = F, Cl, Me):  Structurally Characterized Examples with a Formal Double Bond between Group 14 and 16 Elements Bearing a Halide

Yuqiang Ding, Qingjun Ma, Isabel Usón, +3

Journal of the American Chemical Society

Materials ScienceInorganic ChemistryEngineeringGermanium CentersChemical Bond +10