Martijn J. van Hemert

Zn2+ Inhibits Coronavirus and Arterivirus RNA Polymerase Activity In Vitro and Zinc Ionophores Block the Replication of These Viruses in Cell Culture

Aartjan J.W. te Velthuis, Sjoerd H. E. van den Worm, Amy Sims et al. · PLoS Pathogens · 2010 · 916 citations · Full text

Life Sciences, Biology, Microbiology +17

Genome-wide mapping of SARS-CoV-2 RNA structures identifies therapeutically-relevant elements

Ilaria Manfredonia, Chandran Nithin, Almudena Ponce-Salvatierra et al. · Nucleic Acids Research · 2020 · 313 citations · Full text

Life Sciences, Biology, Infectious Diseases +17

SARS-Coronavirus Replication/Transcription Complexes Are Membrane-Protected and Need a Host Factor for Activity In Vitro

Martijn J. van Hemert, Sjoerd H. E. van den Worm, Kèvin Knoops et al. · PLoS Pathogens · 2008 · 278 citations · Full text

Life Sciences, Microbiology, Molecular Biology +17

Cyclosporin A inhibits the replication of diverse coronaviruses

Adriaan H. de Wilde, Jessika C. Zevenhoven-Dobbe, Yvonne van der Meer et al. · Journal of General Virology · 2011 · 248 citations · Full text

Life Sciences, Infectious Diseases, Molecular Biology +17

Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses

Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov et al. · Journal of the American Chemical Society · 2022 · 244 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17