Matthias Schmuth

Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema

Aileen Sandilands, Ana Terron-Kwiatkowski, Peter Hull et al. · Nature Genetics · 2007 · 660 citations

Allergy, Atopic Dermatitis, Genetic Disorder +11

Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens

Tiffany C. Scharschmidt, Mao‐Qiang Man, Yutaka Hatano et al. · Journal of Allergy and Clinical Immunology · 2009 · 282 citations · Full text

Inflammation, Fibrosis, Signal Transduction +14

Filaggrin Genotype in Ichthyosis Vulgaris Predicts Abnormalities in Epidermal Structure and Function

Robert Gruber, Peter M. Elias, Debra Crumrine et al. · American Journal Of Pathology · 2011 · 234 citations · Full text

Biology, Skin Development, Genetics +7

Peroxisome Proliferator-Activated Receptor (PPAR)-β/δ Stimulates Differentiation and Lipid Accumulation in Keratinocytes

Matthias Schmuth, Christopher M. Haqq, William Cairns et al. · Journal of Investigative Dermatology · 2004 · 226 citations · Full text

Skin Development, Peroxisome Proliferator-activated Receptor, Molecular Physiology +8

Liver X Receptor Activators Display Anti-Inflammatory Activity in Irritant and Allergic Contact Dermatitis Models: Liver-X-Receptor-Specific Inhibition of Inflammation and Primary Cytokine Production

Ashley J. Fowler, Mary Sheu, Matthias Schmuth et al. · Journal of Investigative Dermatology · 2003 · 224 citations · Full text

Inflammation, Primary Cytokine Production, Anti-inflammatory +13