Concepedia

J.R. Luft

JL

Statistics

Publications

11

Citations

476

H-Index

11

Active since

1991

Affiliations

Hauptman-Woodward Medical Research Institute(Current)

Duquesne University

Indiana University – Purdue University Indianapolis

St. Jude Children's Research Hospital

The Medical Foundation

J.R. Luft is an author at Hauptman-Woodward Medical Research Institute specializing in life sciences, biochemistry, and pharmacology.

Publications per year

1991–2005

11

Publications

11

Understanding the role of Leu22 variants in methotrexate resistance: comparison of wild-type and Leu22Arg variant mouse and human dihydrofolate reductase ternary crystal complexes with methotrexate and NADPH

Vivian Cody, J.R. Luft, W. Pangborn · Acta Crystallographica Section D Biological Crystallography · 2005 · 108 citations

, , +17

Methotrexate-resistant variants of human dihydrofolate reductase. Effects of Phe31 substitutions

Srinivas K. Chunduru, Vivian Cody, J.R. Luft et al. · Journal of Biological Chemistry · 1994 · 64 citations · Full text

, , +14

Structure-Based Design and Synthesis of Lipophilic 2,4-Diamino-6-Substituted Quinazolines and Their Evaluation as Inhibitors of Dihydrofolate Reductases and Potential Antitumor Agents

Aleem Gangjee, Anup Vidwans, Anil Vasudevan et al. · Journal of Medicinal Chemistry · 1998 · 62 citations · Full text

, , +13

Automatic classification of sub-microlitre protein-crystallization trials in 1536-well plates

Christian Cumbaa, Angela Lauricella, Nancy Fehrman et al. · Acta Crystallographica Section D Biological Crystallography · 2003 · 50 citations

, , +10

Crystal structure determination at 2.3-A resolution of human transthyretin-3',5'-dibromo-2',4,4',6-tetrahydroxyaurone complex.

Ewa Ciszak, Vivian Cody, J.R. Luft · Proceedings of the National Academy of Sciences · 1992 · 41 citations

, , +17

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