Novel Crohn Disease Locus Identified by Genome-Wide Association Maps to a Gene Desert on 5p13.1 and Modulates Expression of PTGER4

Cécile Libioulle, Édouard Louis, Sarah Hansoul, +19

PLoS Genetics

Genome-wide Association MapsDisease EtiologyGene DesertGeneticsImmunology +18

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

Alexandra–Chloé Villani, Mathieu Lemire, Geneviève Fortin, +18

Nature Genetics

InflammationDisease SusceptibilityAutoimmune DiseaseDisease MechanismMucosal Immunology +7

Purification, characterization, and nucleotide sequence of the thermolabile alpha-amylase from the antarctic psychrotroph Alteromonas haloplanctis A23.

Georges Feller, Thierry Lonhienne, Claude Deroanne, +3

Journal of Biological Chemistry

Active Site FlexibilityThermolabile Alpha-amylaseMolecular BiologyLow Thermal StabilityEnzymatic Modification +14

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease

Yukihide Momozawa, Myriam Mni, Kayo Nakamura, +26

Nature Genetics

InflammationImmunologyPathologyAutoimmunityImmune System +4

An insertion deletion polymorphism in the Interferon Regulatory Factor 5 (IRF5) gene confers risk of inflammatory bowel diseases

Vinciane Dideberg, Guðrún Kristjánsdóttir, Lili Milani, +10

Human Molecular Genetics

GeneticsGenetic EpidemiologyImmunologyPathologyGene Confers Risk +16

The role of the Toll receptor pathway in susceptibility to inflammatory bowel diseases

Philip L. De Jager, Denis Franchimont, Alicja Waliszewska, +24

Genes and Immunity

InflammationChronic Inflammatory DiseasesToll-like ReceptorsToll Receptor PathwayAutoimmune Disease +10

A multi-centre clinico-genetic analysis of the VPS35 gene in Parkinson disease indicates reduced penetrance for disease-associated variants

Manu Sharma, John P. A. Ioannidis, Jan Aasly, +59

Journal of Medical Genetics

Evidence for Significant Overlap between Common Risk Variants for Crohn's Disease and Ankylosing Spondylitis

Debby Laukens, Michel Georges, Cécile Libioulle, +6

PLoS ONE

Genetic Variation in the Familial Mediterranean Fever Gene (MEFV) and Risk for Crohn's Disease and Ulcerative Colitis

Alexandra–Chloé Villani, Mathieu Lemire, Édouard Louis, +20

PLoS ONE

3-years experience review of neonatal screening for hemoglobin disorders using tandem mass spectrometry

François Boemer, Yves Cornet, Cécile Libioulle, +3

Clinica Chimica Acta

Neonatal ScreeningNeonatologyMass SpectrometryPediatricsDiagnosis +7