Prediction of skin permeation by chemical compounds using the artificial membrane, Strat-M™

Takashi Uchida, Wesam R. Kadhum, Sayumi Kanai, +3

European Journal of Pharmaceutical Sciences

Artificial MembraneChemical EngineeringEngineeringChemical CompoundsPorous Membrane +5

Enhancement of skin permeation of high molecular compounds by a combination of microneedle pretreatment and iontophoresis

Xueming Wu, Hiroaki Todo, Kenji Sugibayashi

Journal of Controlled Release

EngineeringMedicineTopical DrugSkin PharmacologyHigh Molecular Compounds +7

Pulmonary Gene Delivery by Chitosan–pDNA Complex Powder Prepared by a Supercritical Carbon Dioxide Process

Hirokazu Okamoto, Seiko Nishida, Hiroaki Todo, +3

Journal of Pharmaceutical Sciences

NanomedicineEngineeringPulmonary Gene DeliveryBiotechnologyNano-drug Delivery +5

Permeation Pathway of Macromolecules and Nanospheres through Skin

Hiroaki Todo, Eriko Kimura, Hirotaka Yasuno, +4

Biological and Pharmaceutical Bulletin

EngineeringPermeation PathwayNanobiotechnologyMedicinePorcine Skin +10

Effect of liquid crystals with cyclodextrin on the bioavailability of a poorly water-soluble compound, diosgenin, after its oral administration to rats

Masaki Okawara, Fumie Hashimoto, Hiroaki Todo, +2

International Journal of Pharmaceutics

Pharmaceutical ScienceBiochemistryPoorly Water-soluble CompoundMedicineOral Administration +4

Measurement of Skin Permeation/Penetration of Nanoparticles for Their Safety Evaluation

Eriko Kimura, Yuichiro Kawano, Hiroaki Todo, +2

Biological and Pharmaceutical Bulletin

NanoparticlesEngineeringNanotoxicologyBiomedical EngineeringDermatology +14

Development of nanoparticles derived from corn as mass producible bionanoparticles with anticancer activity

Daisuke Sasaki, Kosuke Kusamori, Yukiya Takayama, +3

Scientific Reports

Effect of additives on insulin absorption from intratracheally administered dry powders in rats

Hiroaki Todo, Hirokazu Okamoto, Kotaro Iida, +1

International Journal of Pharmaceutics

NutritionInsulin AbsorptionMedicineDiabetesPhysiology +7

Mathematical Model to Predict Skin Concentration of Drugs: Toward Utilization of Silicone Membrane to Predict Skin Concentration of Drugs as an Animal Testing Alternative

Kenji Sugibayashi, Hiroaki Todo, Takeshi Oshizaka, +1

Pharmaceutical Research

EngineeringMedicineDrug PuritySilicone MembraneMathematical Model +7

Transdermal drug delivery by in-skin electroporation using a microneedle array

Keshu Yan, Hiroaki Todo, Kenji Sugibayashi

International Journal of Pharmaceutics

Cell-based Drug DeliveryTopical DrugTransdermal Drug DeliveryWound HealingBiomedical Engineering +4