Interplay of α-synuclein binding and conformational switching probed by single-molecule fluorescence

Allan Chris M. Ferreon, Yann Gambin, Edward A. Lemke, +1

Proceedings of the National Academy of Sciences

Proteinlipid InteractionMolecular BiologyConformational SwitchingSingle Molecule BiophysicsProtein Folding +15

Mechanism of Activation of Protein Kinase JAK2 by the Growth Hormone Receptor

Andrew J. Brooks, Wei Dai, Megan L. O’Mara, +16

Science

Human GrowthMolecular BiologyGrowth Hormone ReceptorSignaling PathwayReceptor Tyrosine Kinase +16

Lateral mobility of proteins in liquid membranes revisited

Yann Gambin, Ricardo López-Esparza, Myriam Reffay, +5

Proceedings of the National Academy of Sciences

SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species

Mehdi Moustaqil, Emma Ollivier, Hsin-Ping Chiu, +10

Emerging Microbes & Infections

Structural basis of TIR-domain-assembly formation in MAL- and MyD88-dependent TLR4 signaling

Thomas Ve, Parimala R. Vajjhala, Andrew Hedger, +17

Nature Structural & Molecular Biology

Signal TransductionNatural SciencesMolecular BiologyGene RegulationStructural Basis +7

Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing

Yann Gambin, Virginia VanDelinder, Allan Chris M. Ferreon, +3

Nature Methods

Single Molecule BiophysicsBiochemistryProtein FoldingNatural SciencesMolecular Biology +6

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

Yann Gambin, Nicholas Ariotti, Kerrie‐Ann McMahon, +16

eLife

Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential

Bjoern Meyer, Jeanne Chiaravalli, Stacy Gellenoncourt, +16

Nature Communications

Single-Molecule Fluorescence Studies of Intrinsically Disordered Proteins

Allan Chris M. Ferreon, Crystal R. Moran, Yann Gambin, +1

Methods in enzymology on CD-ROM/Methods in enzymology

Single-molecule Fluorescence StudiesSingle Molecule BiophysicsProtein FoldingNatural SciencesMolecular Biology +4

Viral M45 and necroptosis‐associated proteins form heteromeric amyloid assemblies

Chi L.L. Pham, Nirukshan Shanmugam, Merryn Strange, +6

EMBO Reports

Viral M45ImmunologyVirologyDegenerative PathologyProtein Misfolding +2