William J. Flosi

Enantioselective Synthesis of Antiinfluenza Compound A-315675

David A. DeGoey, Hui-Ju Chen, William J. Flosi et al. · The Journal of Organic Chemistry · 2002 · 95 citations

Combinatorial Chemistry, Organic Chemistry, Chemistry +16

Water-Soluble Prodrugs of the Human Immunodeficiency Virus Protease Inhibitors Lopinavir and Ritonavir

David A. DeGoey, David J. Grampovnik, William J. Flosi et al. · Journal of Medicinal Chemistry · 2009 · 37 citations

Pharmaceutical Science, Hiv Protease Inhibitors, Immunology +18

2-Pyridyl P1′-Substituted Symmetry-Based Human Immunodeficiency Virus Protease Inhibitors (A-792611 and A-790742) with Potential for Convenient Dosing and Reduced Side Effects

David A. DeGoey, David J. Grampovnik, Charles A. Flentge et al. · Journal of Medicinal Chemistry · 2009 · 30 citations · Full text

Comparator Compounds, Oral Bioavailability, Bioorganic Chemistry +17

Discovery of imidazolidine-2,4-dione-linked HIV protease inhibitors with activity against lopinavir-resistant mutant HIV

William J. Flosi, David A. DeGoey, David J. Grampovnik et al. · Bioorganic & Medicinal Chemistry · 2006 · 27 citations

Medicine, Drug Discovery, Antiviral Drug Development +9

Synthesis of the 3a-(3-Indolyl)-1,2,3,3a,8,8a-hexahydropyrrolo-[2,3-b]indole Core of Leptosins D-F

David Crich, Ewa Fredette, William J. Flosi · Heterocycles · 1998 · 14 citations · Full text

Lepfoshaaeria Sp, Biosynthesis, Engineering +12