Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

David E. Gordon, Joseph Hiatt, Mehdi Bouhaddou, +303

Science

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Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant

Xianding Deng, Miguel Garcia-Knight, Mir M. Khalid, +43

Cell

Viral PathogenesisImmunologyVirologyViral Structural ProteinVirus Transmission +2

An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike

Michael Schoof, Bryan Faust, Reuben A. Saunders, +143

Science

Materials ScienceTrivalent NanobodySpike ProteinEngineeringNanotechnology +8

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses

Ruofan Wang, Camille R. Simoneau, Jessie Kulsuptrakul, +17

Cell

Viral EvolutionViral DiagnosticsCommon Cold CoronavirusesPathogenesisImmunology +3

SARS-CoV-2 infection of human iPSC–derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19

Juan A. Pérez-Bermejo, Sarah J. Rockwood, Camille R. Simoneau, +14

Science Translational Medicine

Coronavirus Disease 2019Cardiac MuscleNuclear DisruptionCardiomyopathyLong Covid +11

Transmission, infectivity, and antibody neutralization of an emerging SARS-CoV-2 variant in California carrying a L452R spike protein mutation

Xianding Deng, Miguel Garcia-Knight, Mir M. Khalid, +43

Androgen Signaling Regulates SARS-CoV-2 Receptor Levels and Is Associated with Severe COVID-19 Symptoms in Men

Ryan M. Samuel, Homa Majd, Mikayla N Richter, +21

Cell stem cell

Is AssociatedLong CovidCovid-19 PandemicImmunologySevere Covid-19 Symptoms +3

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

Wilfredo F. García-Beltrán, Angelique Hölzemer, Glòria Martrus, +13

Nature Immunology

Signal TransductionG Protein-coupled ReceptorImmunologyReceptor (Biochemistry)Molecular Biology +7

Limited cross-variant immunity from SARS-CoV-2 Omicron without vaccination

Rahul K. Suryawanshi, Irene P. Chen, Tongcui Ma, +40

Nature

Tropism of SARS-CoV-2 for human cortical astrocytes

Madeline G. Andrews, Tanzila Mukhtar, Ugomma C. Eze, +25

Proceedings of the National Academy of Sciences

InflammationCortical AstrocytesNeurovirologyInfected AstrocytesHuman Cortical Astrocytes +13