Lan Trinh

Design, synthesis, and in vitro biological activity of benzimidazole based factor Xa inhibitors

Zuchun Zhao, Damian O. Arnaiz, Brian D. Griedel et al. · Bioorganic & Medicinal Chemistry Letters · 2000 · 104 citations · Full text

Medicinal Chemistry, Biochemistry, Antiparasitic Agent +9

Discovery of <i>N</i>-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3,5-difluoro- 6-[3-(4,5-dihydro-1-methyl-1<i>H</i>-imidazol-2-yl)phenoxy]pyridin-4-yl]-<i>N</i>-methylglycine (ZK-807834):  A Potent, Selective, and Orally Active Inhibitor of the Blood Coagulation Enzyme Factor Xa

Gary B. Phillips, Brad O. Buckman, David D. Davey et al. · Journal of Medicinal Chemistry · 1998 · 63 citations · Full text

Pharmaceutical Science, Altmetric Attention Score, Pharmacotherapy +16

Design, synthesis, and biological activity of novel purine and bicyclic pyrimidine factor Xa inhibitors

Brad O. Buckman, Raju Mohan, Sunil Koovakkat et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 55 citations · Full text

Biological Activity, Combinatorial Chemistry, Biochemistry +9

Structure–Activity relationships of substituted benzothiophene-anthranilamide factor Xa inhibitors

Yuo-Ling Chou, David D. Davey, Keith Eagen et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 40 citations · Full text

Molecular Pharmacology, Medicine, Rational Drug Design +4

Design, Synthesis, and Activity of 2,6-Diphenoxypyridine-Derived Factor Xa Inhibitors

Gary B. Phillips, David D. Davey, Keith Eagen et al. · Journal of Medicinal Chemistry · 1999 · 37 citations · Full text

Bovine Trypsin, Protein Chemistry, Medicinal Chemistry +13