Stefan Siwko

LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption

Jian Luo, Zhengfeng Yang, Yu Ma et al. · Nature Medicine · 2016 · 356 citations

Developmental Biology, Bone Resorption, Bone Morphogenic Protein +11

Dual base editor catalyzes both cytosine and adenine base conversions in human cells

Xiaohui Zhang, Biyun Zhu, Liang Chen et al. · Nature Biotechnology · 2020 · 287 citations

Cellular Enzymology, Biochemistry, Adenine Base Conversions +11

Genome-wide transcriptome profiling of homologous recombination DNA repair

Guang Peng, Curtis Chun-Jen Lin, Wei Mo et al. · Nature Communications · 2014 · 226 citations · Full text

Genome Instability, Genetics, Dna Replication +4

Inhibition of Rspo-Lgr4 Facilitates Checkpoint Blockade Therapy by Switching Macrophage Polarization

Binghe Tan, Xiujuan Shi, Jie Zhang et al. · Cancer Research · 2018 · 155 citations

Re-engineering the adenine deaminase TadA-8e for efficient and specific CRISPR-based cytosine base editing

Liang Chen, Biyun Zhu, Gaomeng Ru et al. · Nature Biotechnology · 2022 · 148 citations

Engineering, Genome Surgery, Genetic Engineering +10