U. KRUEGER

(H+, K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate

Bernhard Kohl, Ernst Sturm, Joerg Senn‐Bilfinger et al. · Journal of Medicinal Chemistry · 1992 · 68 citations · Full text

(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 2. The reaction cascade induced by treatment with acids. Formation of 5H-pyrido[1',2':4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium salts and their reactions with thiols

Joerg Senn‐Bilfinger, U. KRUEGER, Ernst Sturm et al. · The Journal of Organic Chemistry · 1987 · 48 citations

Inhibitory Activity, Medicinal Chemistry, Biochemistry +11

(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 1. Their reaction with thiols under acidic conditions. Disulfide containing 2-pyridiniobenzimidazolides as mimics for the inhibited enzyme

Ernst Sturm, U. KRUEGER, Joerg Senn‐Bilfinger et al. · The Journal of Organic Chemistry · 1987 · 44 citations

Biochemistry, Acidic Conditions, Inhibited Enzyme +12

(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 3. Evidence for the involvement of a sulfenic acid in their reactions

U. KRUEGER, Joerg Senn‐Bilfinger, Ernst Sturm et al. · The Journal of Organic Chemistry · 1990 · 17 citations

Molecular Pharmacology, Medicinal Chemistry, Molecular Sciences +13