Ernst Sturm

(H+, K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate

Bernhard Kohl, Ernst Sturm, Joerg Senn‐Bilfinger et al. · Journal of Medicinal Chemistry · 1992 · 68 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Hydroxyl radical scavenging reactivity of proton pump inhibitors

Wolfgang Simon, Ernst Sturm, Hans‐Jürgen Hartmann et al. · Biochemical Pharmacology · 2006 · 54 citations

Life Sciences, Medicinal Chemistry, Pharmacology +10

(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 2. The reaction cascade induced by treatment with acids. Formation of 5H-pyrido[1',2':4,5][1,2,4]thiadiazino[2,3-a]benzimidazol-13-ium salts and their reactions with thiols

Joerg Senn‐Bilfinger, U. KRUEGER, Ernst Sturm et al. · The Journal of Organic Chemistry · 1987 · 48 citations

Life Sciences, Biochemistry, Chemistry +8

(H+-K+)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 1. Their reaction with thiols under acidic conditions. Disulfide containing 2-pyridiniobenzimidazolides as mimics for the inhibited enzyme

Ernst Sturm, U. KRUEGER, Joerg Senn‐Bilfinger et al. · The Journal of Organic Chemistry · 1987 · 44 citations

Life Sciences, Biochemistry, Pharmacology +13

Acid activation of (H⁺–K⁺)-ATPase inhibiting 2-(2-pyridylmethyl-sulphinyl)benzimidazoles: isolation and characterization of the thiophilic ‘active principle’ and its reactions

Volker Figala, Kurt Klemm, Bernhard Kohl et al. · Journal of the Chemical Society Chemical Communications · 1986 · 43 citations

Life Sciences, Biochemistry, Chemistry +11