Massive CA1/2 Neuronal Loss with Intraneuronal and N-Terminal Truncated Aβ42 Accumulation in a Novel Alzheimer Transgenic Model

Caty Casas, Nicolas Sergeant, Jean‐Michel Itier, +17

American Journal Of Pathology

Synaptic PlasticityNeurodegenerative DiseasesMolecular NeuroscienceAlzheimer's DiseaseSynaptic Signaling +11

Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice

Véronique Blanchard, Saliha Moussaoui, Christian Czech, +12

Experimental Neurology

Neurodegenerative DiseasesTime SequenceMolecular NeuroscienceDevelopmental BiologyAβ Deposits +8

Inhibition by riluzole of electrophysiological responses mediated by rat kainate and NMDA receptors expressed in Xenopus oocytes

Marc-Williams Debono, Joëlle Le Guern, Thierry Canton, +2

European Journal of Pharmacology

Xenopus OocytesMolecular PhysiologyHyperpolarization (Biology)NeurophysiologyMedicine +11

RPR 119990, a novel alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid antagonist: synthesis, pharmacological properties, and activity in an animal model of amyotrophic lateral sclerosis.

Thierry Canton, Böhme Ga, Alain Boireau, +16

PubMed

NeurotransmitterBrain PenetrationRpr 119990Experimental PharmacologyNeurology +15

Glutamate uptake is decreased tardively in the spinal cord of FALS mice

Thierry Canton, Jeremy Pratt, Jean‐Marie Stutzmann, +2

Neuroreport

Glutamate Uptake DeficiencyNeurotransmitterNeurologyNeuropathologyNeurochemistry +14

RPR 119990, a Novel α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Antagonist: Synthesis, Pharmacological Properties, and Activity in an Animal Model of Amyotrophic Lateral Sclerosis

Thierry Canton, Georg Andrees Böhme, Alain Boireau, +16

Journal of Pharmacology and Experimental Therapeutics

SAR228810: an antibody for protofibrillar amyloid β peptide designed to reduce the risk of amyloid-related imaging abnormalities (ARIA)

Laurent Pradier, Véronique Blanchard-Brégeon, Andrees Bohme, +22

Alzheimer s Research & Therapy

Evidence for a coupling between dopaminergic receptors and phospholipid methylation in mouse B lymphocytes

G. Le Fur, T. Phan, Thierry Canton, +2

Life Sciences

Functional SelectivityMedicineImmunologyReceptor (Biochemistry)Phospholipid Methylation +7

The mechanism of action of zopiclone

Adam Doble, Thierry Canton, C. Malgouris, +5

European Psychiatry

A Rapid Filtration Assay for the Glycine Binding Site on the NMDA Receptor in Rat Cortical Membranes using [3H]Dichlorokynurenic Acid

Thierry Canton, Adam Doble, Jean-Marie Miquet, +2

Journal of Pharmacy and Pharmacology

Rapid Filtration AssayPharmacotherapyBinding SiteNeurochemistryBiochemistry +15