Haruka Takata

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice

Sherif E. Emam, Nehal E. Elsadek, Amr S. Abu Lila et al. · Journal of Controlled Release · 2021 · 77 citations

Blood Clearance Phenomenon, Pegylated Exosomes, Hematology +11

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon

Marwa Mohamed El Sayed, Haruka Takata, Taro Shimizu et al. · Journal of Controlled Release · 2020 · 50 citations

Inflammation, Accelerated Blood Clearance, Autoimmune Disease +11

Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice

Nehal E. Elsadek, Amr S. Abu Lila, Sherif E. Emam et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 38 citations

Accelerated Blood Clearance, Autoimmune Disease, Medicine +7

Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route

Haruka Takata, Taro Shimizu, Rina Yamade et al. · Journal of Controlled Release · 2023 · 29 citations

Lipid Preparation, Immunology, Endocytic Pathway +7

Impact of Pre-Existing or Induced Anti-PEG IgM on the Pharmacokinetics of Peginterferon Alfa-2a (Pegasys) in Mice

Nehal E. Elsadek, Eri Hondo, Taro Shimizu et al. · Molecular Pharmaceutics · 2020 · 28 citations

Circulation Half-lives, Immunology, Biological Therapy +19