Nehal E. Elsadek

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice

Sherif E. Emam, Nehal E. Elsadek, Amr S. Abu Lila et al. · Journal of Controlled Release · 2021 · 82 citations

Life Sciences, Immunology, Pharmacokinetics +5

Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues

Sherif E. Emam, Amr S. Abu Lila, Nehal E. Elsadek et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2019 · 75 citations

Medicine, Cancer Biology, Oncology +17

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon

Marwa Mohamed El Sayed, Haruka Takata, Taro Shimizu et al. · Journal of Controlled Release · 2020 · 51 citations

Life Sciences, Immunology, Pathology +11

Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice

Nehal E. Elsadek, Amr S. Abu Lila, Sherif E. Emam et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 42 citations

Medicine, Immunology, Pharmacology +5

Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route

Haruka Takata, Taro Shimizu, Rina Yamade et al. · Journal of Controlled Release · 2023 · 36 citations

Pharmacy, Biochemistry, Immunology +9