Johanna Fälting

A zebrafish model of tauopathy allows in vivo imaging of neuronal cell death and drug evaluation

Dominik Paquet, Ratan V. Bhat, Astrid Sydow et al. · Journal of Clinical Investigation · 2009 · 273 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson et al. · Journal of Biological Chemistry · 2012 · 138 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

AZD3293: A Novel, Orally Active BACE1 Inhibitor with High Potency and Permeability and Markedly Slow Off-Rate Kinetics

Susanna Eketjäll, Juliette Janson, Karin Kaspersson et al. · Journal of Alzheimer s Disease · 2016 · 131 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

<scp>AZD</scp>1080, a novel <scp>GSK</scp>3 inhibitor, rescues synaptic plasticity deficits in rodent brain and exhibits peripheral target engagement in humans

Biljana Georgievska, Johan Sandin, James Doherty et al. · Journal of Neurochemistry · 2013 · 118 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Design and Synthesis of β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors with in Vivo Brain Reduction of β-Amyloid Peptides

Britt‐Marie Swahn, Karin Kolmodin, Sofia Karlström et al. · Journal of Medicinal Chemistry · 2012 · 100 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17