Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Ziming Wang, Ethan G. Aguilar, Jesus I. Luna, +30

Nature Medicine

ObesityCancer ImmunosurveillancePd-1 Checkpoint BlockadeT Cell FunctionMedicine +8

Neurological manifestations of SARS-CoV-2 infection in hospitalised children and adolescents in the UK: a prospective national cohort study

Stephen Ray, Omar Abdel‐Mannan, Mário Sá, +51

The Lancet Child & Adolescent Health

Pediatric EpidemiologyNeurovirologySars-cov-2 InfectionHospitalised ChildrenHealthcare-associated Infection +9

Minimal PD-1 expression in mouse and human NK cells under diverse conditions

Sean J. Judge, Cordelia Dunai, Ethan G. Aguilar, +13

Journal of Clinical Investigation

Adaptive Immune SystemT-regulatory CellImmunologyImmunoeditingPathology +18

Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation

Lam T. Khuat, Catherine T. Le, Chien-Chun Steven Pai, +24

Science Translational Medicine

Para-infectious brain injury in COVID-19 persists at follow-up despite attenuated cytokine and autoantibody responses

Benedict Michael, Cordelia Dunai, Edward Needham, +42

Nature Communications

Licensing delineates helper and effector NK cell subsets during viral infection

Anthony E. Zamora, Ethan G. Aguilar, Can M. Sungur, +10

JCI Insight

Adaptive Immune SystemImmunologyImmune RegulationImmunodominanceViral Infection +21

Skin-Resident β2AR Signaling Delays Burn Wound Healing

Alan V. Nguyen, Sofia Caryotakis, Marilyn Wang, +7

Journal of Investigative Dermatology

PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment

Catherine T. Le, Lam T. Khuat, Sofia Caryotakis, +9

Frontiers in Immunology

Clinical SymptomsT-regulatory CellImmunologyImmune RegulationPathology +16

Increased efficacy of dual proinflammatory cytokine blockade on acute GVHD while maintaining GVT effects

Lam T. Khuat, Logan V. Vick, Cordelia Dunai, +14

Blood

IL-2 and Anti-TGF-β Promote NK Cell Reconstitution and Anti-tumor Effects after Syngeneic Hematopoietic Stem Cell Transplantation

Maite Álvarez, Cordelia Dunai, Lam T. Khuat, +3

Cancers

Cell TherapyImmunologyImmune RegulationImmunoeditingCell Replacement Therapy +22