Mario G. Mirisola

Low Protein Intake Is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population

Morgan E. Levine, Jorge Suárez, Sebastian Brandhorst et al. · Cell Metabolism · 2014 · 907 citations · Full text

Agriculture, Nutrition, Nutritional Sciences +17

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan

Sebastian Brandhorst, In Young Choi, Min Wei et al. · Cell Metabolism · 2015 · 870 citations · Full text

Life Sciences, Nutritional Sciences, Physiology +13

Prolonged Fasting Reduces IGF-1/PKA to Promote Hematopoietic-Stem-Cell-Based Regeneration and Reverse Immunosuppression

Chia‐Wei Cheng, Gregor B. Adams, Laura Perin et al. · Cell stem cell · 2014 · 488 citations · Full text

Life Sciences, Cell Biology, Hematology +16

Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging

Mario G. Mirisola, Giusi Taormina, Paola Fabrizio et al. · PLoS Genetics · 2014 · 88 citations · Full text

Life Sciences, Biochemistry, Physiology +16

RAS residues that are distant from the GDP binding site play a critical role in dissociation factor‐stimulated release of GDP.

Arturo C. Verrotti, Jean‐Bernard Créchet, Francesco Di Blasi et al. · The EMBO Journal · 1992 · 56 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +9