Derek M. Shore

Pregnenolone Can Protect the Brain from Cannabis Intoxication

Monique Vallée, S. Vitiello, Luigi Bellocchio et al. · Science · 2014 · 309 citations · Full text

Identification of the GPR55 Antagonist Binding Site Using a Novel Set of High-Potency GPR55 Selective Ligands

Evangelia Kotsikorou, Haleli Sharir, Derek M. Shore et al. · Biochemistry · 2013 · 99 citations

Drug Target, Gpr55 Antagonists, Molecular Pain +18

Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor

Derek M. Shore, Gemma L. Baillie, Dow P. Hurst et al. · Journal of Biological Chemistry · 2013 · 68 citations · Full text

Cannabis Use, Org27569-binding Site Overlaps, Biochemistry +13

A Machine Learning Approach for the Discovery of Ligand-Specific Functional Mechanisms of GPCRs

Ambrose Plante, Derek M. Shore, Giulia Morra et al. · Molecules · 2019 · 66 citations · Full text

CD19 CAR antigen engagement mechanisms and affinity tuning

Changhao He, Jorge Mansilla‐Soto, Nandish Khanra et al. · Science Immunology · 2023 · 61 citations · Full text

Chimeric Antigen Receptor, Car T Cells, Cancer Immunosurveillance +14