Thomas Ruch

Engineering an Amine Transaminase for the Efficient Production of a Chiral Sacubitril Precursor

Scott J. Novick, Nikki Dellas, Ravi Garcia et al. · ACS Catalysis · 2021 · 78 citations · Full text

Enzyme Variant, Biosynthesis, Amine Transaminase +15

Application of Transition-Metal Catalysis, Biocatalysis, and Flow Chemistry as State-of-the-Art Technologies in the Synthesis of LCZ696

Xingxian Gu, Jibin Zhao, Like Chen et al. · The Journal of Organic Chemistry · 2020 · 36 citations

Heart Failure, Engineering, Organic Chemistry +17

Synthesis, Characterization, and Electrochemical and Photophysical Properties of Rhenium(I) and ruthenium(II) complexes of 2,2′‐bipyridine ligand functionalized β‐cyclodextrins

Robert Deschenaux, Thomas Ruch, Pierre‐François Deschenaux et al. · Helvetica Chimica Acta · 1995 · 32 citations

Inorganic Chemistry, Chemical Engineering, Engineering +11

Toward a Scalable Synthesis and Process for EMA401, Part III: Using an Engineered Phenylalanine Ammonia Lyase Enzyme to Synthesize a Non-natural Phenylalanine Derivative

Leo A. Hardegger, Pascal Beney, Dominique Bixel et al. · Organic Process Research & Development · 2020 · 28 citations

Engineering, Part Iii, Molecular Biology +21

From Cycloolefins to LinearC2-Symmetrical 1,4-Diamino-2,3-diol Building Blocks—Peptide Mimetics, Biocatalysis, and Pinacol Coupling ofα-Amino Aldehydes

Joachim Armbruster, S Grabowski, Thomas Ruch et al. · Angewandte Chemie International Edition · 1998 · 19 citations