Edward J.N. Ishac

Inhibition of exocytotic noradrenaline release by presynaptic cannabinoid CB¹receptors on peripheral sympathetic nerves

Edward J.N. Ishac, Kristy D. Lake, K Varga et al. · British Journal of Pharmacology · 1996 · 345 citations · Full text

Life Sciences, Neurobiology, Pharmacology +17

Elevated interleukin-6 during ethanol consumption acts as a potential endogenous protective cytokine against ethanol-induced apoptosis in the liver: involvement of induction of Bcl-2 and Bcl-xL proteins

Won–Ho Kim, Zhigang Tian, Barbara Jaruga et al. · Oncogene · 2002 · 181 citations

Pharmacy, Cell Biology, Toxicology +17

Effects of ethanol on mitogen-activated protein kinase and stress-activated protein kinase cascades in normal and regenerating liver

Jianping Chen, Edward J.N. Ishac, Paul Dent et al. · Biochemical Journal · 1998 · 109 citations · Full text

Medicine, Cell Biology, Pharmacology +15

Differential Regulation of the Mitogen-Activated Protein and Stress-Activated Protein Kinase Cascades by Adrenergic Agonists in Quiescent and Regenerating Adult Rat Hepatocytes

Mark S. Spector, Kelly L. Auer, W. David Jarvis et al. · Molecular and Cellular Biology · 1997 · 107 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

Interferons activate the p42/44 mitogen-activated protein kinase and JAK-STAT (Janus kinase-signal transducer and activator transcription factor) signalling pathways in hepatocytes: differential regulation by acute ethanol via a protein kinase C-dependent mechanism

Jianping Chen, Feng Hong, Edward J.N. Ishac et al. · Biochemical Journal · 2000 · 67 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17