Eddie C.‐K. Liu

The Discovery of Sulfonamide Endothelin Antagonists and the Development of the Orally Active ETA Antagonist 5-(Dimethylamino)-N-(3,4-dimethyl-5- isoxazolyl)-1-naphthalenesulfonamide

Philip D. Stein, John T. Hunt, David Floyd et al. · Journal of Medicinal Chemistry · 1994 · 137 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +7

Biphenylsulfonamide Endothelin Receptor Antagonists. 4. Discovery of <i>N</i>-[[2‘-[[(4,5-Dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1‘-biphenyl]- 2-yl]methyl]-<i>N</i>,3,3-trimethylbutanamide (BMS-207940), A Highly Potent and Orally Active ET_A Selective Antagonist

Natesan Murugesan, Zhengxiang Gu, Steven H. Spergel et al. · Journal of Medicinal Chemistry · 2002 · 63 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The endothelin receptor antagonist, BQ-123, inhibits angiotensin II-induced contractions in rabbit aorta

Maria L. Webb, Kenneth E.J. Dickinson, Carol L. Delaney et al. · Biochemical and Biophysical Research Communications · 1992 · 57 citations

Life Sciences, Pharmacology, Physiology +7

Molecular characterization of angiotensin II type II receptors in rat pheochromocytoma cells

Maria L. Webb, Eddie C.‐K. Liu, Robert Cohen et al. · Peptides · 1992 · 55 citations

Life Sciences, Molecular Biology, Pharmacology +11

BMS-182874 is a selective, nonpeptide endothelin ETA receptor antagonist.

Marjorie Webb, J. Eileen Bird, Eddie C.‐K. Liu et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 41 citations

Life Sciences, Pharmacology, Physiology +15