Robert Mate

Discovery and Evaluation of BMS-708163, a Potent, Selective and Orally Bioavailable γ-Secretase Inhibitor

Kevin W. Gillman, John E. Starrett, Michael F. Parker et al. · ACS Medicinal Chemistry Letters · 2010 · 183 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +19

Discovery of the first antibacterial small molecule inhibitors of MurB

Joanne J. Bronson, Kenneth DenBleyker, Paul Falk et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 88 citations

Medicine, Antibacterial Agent, Antimicrobial Chemotherapy +7

Discovery of isoxazolinone antibacterial agents. Nitrogen as a replacement for the stereogenic center found in oxazolidinone antibacterials

Lawrence B. Snyder, Zhaoxing Meng, Robert Mate et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 42 citations

Bioorganic Chemistry, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +16

Discovery of a novel series of quinolone α7 nicotinic acetylcholine receptor agonists

Ivar M. McDonald, Robert Mate, F. Christopher Zusi et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 24 citations · Full text

Molecular Pharmacology, Novel Series, Biochemistry +5

Design and Synthesis of a New Series of 4-Heteroarylamino-1′-azaspiro[oxazole-5,3′-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure–Activity Relationship

James A. Cook, F. Christopher Zusi, Ivar M. McDonald et al. · Journal of Medicinal Chemistry · 2016 · 18 citations · Full text