Concepedia

Peter Mikochik

PM

6

Publications

410

Citations

6

H-Index

2007

Active since

Affiliations

Pfizer (United States)(Current)

WuXi AppTec (China)

Peter Mikochik is an author at Pfizer (United States) specializing in medicine, molecular modeling, and transcriptional regulation.

Top concepts

MedicineBiochemistryCell BiologyPharmacologyTumor BiologyCell SignalingDrug DiscoveryPeptide SciencePharmacotherapySmall Molecules

Publications per year

2007–2023

6

Publications

6

Peptide-Catalyzed Kinetic Resolution of Formamides and Thioformamides as an Entry to Nonracemic Amines

Brandon Fowler, Peter Mikochik, Scott J. Miller · Journal of the American Chemical Society · 2010 · 103 citations · Full text

HIV Protease Inhibitor Nelfinavir Inhibits Growth of Human Melanoma Cells by Induction of Cell Cycle Arrest

Wei Jiang, Peter Mikochik, Jin H. et al. · Cancer Research · 2007 · 85 citations · Full text

Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors

Michael A. Brodney, Elizabeth M. Beck, Christopher R. Butler et al. · Journal of Medicinal Chemistry · 2015 · 78 citations · Full text

Reduce Risk, Drug Target, Peptide Science +21

Modulating Androgen Receptor-Driven Transcription in Prostate Cancer with Selective CDK9 Inhibitors

André Richters, Shelby K. Doyle, David B. Freeman et al. · Cell chemical biology · 2020 · 78 citations · Full text

Androgen Receptor, Androgen Receptor-driven Transcription, Tumor Biology +16

Discovery of KB-0742, a Potent, Selective, Orally Bioavailable Small Molecule Inhibitor of CDK9 for MYC-Dependent Cancers

David B. Freeman, Tamara D. Hopkins, Peter Mikochik et al. · Journal of Medicinal Chemistry · 2023 · 36 citations · Full text

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