Recognition, Neutralization, and Clearance of Target Peptides in the Bloodstream of Living Mice by Molecularly Imprinted Polymer Nanoparticles: A Plastic Antibody

Yu Hoshino, Hiroyuki Koide, Takeo Urakami, +4

Journal of the American Chemical Society

NanoparticlesNanomedicineEngineeringTarget Peptide ToxinPeptide Engineering +11

The rational design of a synthetic polymer nanoparticle that neutralizes a toxic peptide in vivo

Yu Hoshino, Hiroyuki Koide, Keiichi Furuya, +6

Proceedings of the National Academy of Sciences

A polymer nanoparticle with engineered affinity for a vascular endothelial growth factor (VEGF165)

Hiroyuki Koide, Keiichi Yoshimatsu, Yu Hoshino, +10

Nature Chemistry

NanoparticlesAngiogenesisEngineeringPolymer NanoparticleEngineered Affinity +4

Particle size-dependent triggering of accelerated blood clearance phenomenon

Hiroyuki Koide, Tomohiro Asai, Kentaro Hatanaka, +8

International Journal of Pharmaceutics

ThrombosisMedicineFluid MechanicsPhysiologyHematology +7

T cell-independent B cell response is responsible for ABC phenomenon induced by repeated injection of PEGylated liposomes

Hiroyuki Koide, Tomohiro Asai, Kentaro Hatanaka, +7

International Journal of Pharmaceutics

Signal TransductionT-regulatory CellAbc PhenomenonImmunologyRepeated Injection +10

Combination therapy with liposomal neuroprotectants and tissue plasminogen activator for treatment of ischemic stroke

Tatsuya Fukuta, Tomohiro Asai, Yosuke Yanagida, +4

The FASEB Journal

Design of Synthetic Polymer Nanoparticles that Capture and Neutralize a Toxic Peptide

Yu Hoshino, Takeo Urakami, Takashi Kodama, +4

Small

NanoparticlesNanomedicineBinding CapacityEngineeringProtein Nanoparticles +10

Synthetic hydrogel nanoparticles for sepsis therapy

Hiroyuki Koide, Anna Okishima, Yu Hoshino, +11

Nature Communications

Wear of the AFM diamond tip sliding against silicon

Andrei Khurshudov, Hiroyuki Koide

Wear

Afm Diamond TipEngineeringSliding WearApplied PhysicsWear-resistant Material +2

Systemic Administration of siRNA with Anti-HB-EGF Antibody-Modified Lipid Nanoparticles for the Treatment of Triple-Negative Breast Cancer

Ayaka Okamoto, Tomohiro Asai, Yusuke Hirai, +4

Molecular Pharmaceutics

NanoparticlesBreast OncologyNanotherapeuticsEngineeringLipid Nanoparticles +21