t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

H Miyoshi, K Shimizu, T Kozu, +3

Proceedings of the National Academy of Sciences

Mixed-phenotype Acute LeukemiaGeneticsEpigeneticsMyeloid NeoplasiaHematological Malignancy +17

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

Hiroyuki Miyoshi, T Kozu, Kimiko Shimizu, +5

The EMBO Journal

Hematological MalignancyChromatinImmunologyHematologyAml1-mtg8 Fusion Transcript +4

Phase I/II Study of Concurrent Chemoradiotherapy for Localized Nasal Natural Killer/T-Cell Lymphoma: Japan Clinical Oncology Group Study JCOG0211

Motoko Yamaguchi, Kensei Tobinai, Masahiko Oguchi, +17

Journal of Clinical Oncology

Different karyotypic patterns in early and advanced stage neuroblastomas.

Yasuhiko Kaneko, N Kanda, Nobuo Maseki, +4

PubMed

N-myc AmplificationRadiation OncologyTumoral PathologyCytogeneticsExcellent Prognosis +12

A novel translocation, t(2;5)(p23;q35), in childhood phagocytic large T- cell lymphoma mimicking malignant histiocytosis

Yasuhiko Kaneko, Glauco Frizzera, S Edamura, +7

Blood

There may be two tumor suppressor genes on chromosome arm Ip closely associated with biologically distinct subtypes of neuroblastoma

Osamu Takeda, Chieko Homma, Nobuo Maseki, +5

Genes Chromosomes and Cancer

Clinical and hematologic characteristics in acute leukemia with 11q23 translocations

Yasuhiko Kaneko, Nobuo Maseki, Nobuko Takasaki, +7

Blood

An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation.

Katsuhiko Shimizu, Hitoshi Ichikawa, Arinobu Tojo, +6

Proceedings of the National Academy of Sciences

Erg GeneEts-related GeneCytogeneticsMixed-phenotype Acute LeukemiaGenetics +14

Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.

Xiao–Tang Kong, Kohmei Ida, Hitoshi Ichikawa, +16

PubMed

Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction

T Kozu, Hiroyuki Miyoshi, K Shimizu, +5

Blood