t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.

H Miyoshi, K Shimizu, T Kozu, +3

Proceedings of the National Academy of Sciences

Mixed-phenotype Acute LeukemiaGeneticsEpigeneticsMyeloid NeoplasiaHematological Malignancy +17

The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.

Hiroyuki Miyoshi, T Kozu, Kimiko Shimizu, +5

The EMBO Journal

Hematological MalignancyChromatinImmunologyHematologyAml1-mtg8 Fusion Transcript +4

Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction

T Kozu, Hiroyuki Miyoshi, K Shimizu, +5

Blood

Heterogeneous nuclear ribonucleoprotein B1 as a new marker of early detection for human lung cancers.

Eisaburo Sueoka, Yuri Goto, Naoko Sueoka, +3

PubMed

PathologyCancer BiologySplicing VariantNucleic Acid BiomarkersTumor Biology +16

Mouse DNA replicase. DNA polymerase associated with a novel RNA polymerase activity to synthesize initiator RNA of strict size.

Tatsuo Yagura, T Kozu, Tetsuzo Seno

Journal of Biological Chemistry

Expression of the tumor necrosis factor? gene and early response genes by nodularin, a liver tumor promoter, in primary cultured rat hepatocytes

Eisaburo Sueoka, Naoko Sueoka, Sachiko Okabe, +7

Journal of Cancer Research and Clinical Oncology

ImmunologyPathologyCell DeathCirrhosisInflammation +16

Consistent disruption of the AML1 gene occurs within a single intron in the t(8;21) chromosomal translocation.

Kimiko Shimizu, Hiroyuki Miyoshi, T Kozu, +5

PubMed

CytogeneticsMixed-phenotype Acute LeukemiaGeneticsMolecular GeneticsConsistent Disruption +18

Increase in dATP pool in aphidicolin-resistant mutants of mouse FM3A cells

Dai Ayusawa, Kimiko Iwata, T Kozu, +2

Biochemical and Biophysical Research Communications

Knockout MouseDatp PoolGeneticsMouse Fm3a CellsAphidicolin-resistant Mutants +7

Novel form of DNA polymerase alpha associated with DNA primase activity of vertebrates. Detection with mouse stimulating factor.

Tatsuo Yagura, T Kozu, Tetsuzo Seno, +3

Journal of Biological Chemistry

Tight association of DNA primase with a subspecies of mouse DNA polymerase alpha.

Tatsuo Yagura, S. Tanaka, T Kozu, +2

Journal of Biological Chemistry

Dna Primase ActivityDna SequencingNatural SciencesGeneticsDna Analysis +13