William F. Simonds

Ras-dependent activation of MAP kinase pathway mediated by G-protein βγ subunits

Piero Crespo, Ningzhi Xu, William F. Simonds et al. · Nature · 1994 · 814 citations

Signal Transduction, Molecular Physiology, Cell Regulation +12

HRPT2, encoding parafibromin, is mutated in hyperparathyroidism–jaw tumor syndrome

John D. Carpten, Christiane M. Robbins, Andrea Villablanca et al. · Nature Genetics · 2002 · 742 citations

Parathyroid Hormone, Parathyroid Disease, Pathology +2

Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies.

William F. Simonds, Paul K. Goldsmith, Juan Codina et al. · Proceedings of the National Academy of Sciences · 1989 · 374 citations · Full text

Alpha 2-Adrenergic Inhibition, Immunology, Glycobiology +23

Signaling from G Protein-coupled Receptors to c-Jun Kinase Involves βγ Subunits of Heterotrimeric G Proteins Acting on a Ras and Rac1-dependent Pathway

Omar A. Coso, Hidemi Teramoto, William F. Simonds et al. · Journal of Biological Chemistry · 1996 · 247 citations · Full text

Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment.

Teresa L.Z. Jones, William F. Simonds, John J. Merendino et al. · Proceedings of the National Academy of Sciences · 1990 · 227 citations · Full text

Molecular Biology, Alpha Subunits, Membrane Attachment +18