Julien Verrax

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Pierre Sonveaux, Frédérique Végran, Thies Schroeder et al. · Journal of Clinical Investigation · 2008 · 1.6K citations · Full text

Chemoprevention Strategy, Metabolic Remodeling, Cancer Biology +18

Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis

Pierre Sonveaux, Tamara Copetti, Christophe J. De Saedeleer et al. · PLoS ONE · 2012 · 511 citations · Full text

Endothelial Cells, Lactate Influx, Metabolic Remodeling +19

Gut microbiota-derived propionate reduces cancer cell proliferation in the liver

Laure B. Bindels, Paolo E. Porporato, Evelyne Dewulf et al. · British Journal of Cancer · 2012 · 298 citations · Full text

Restoring Specific Lactobacilli Levels Decreases Inflammation and Muscle Atrophy Markers in an Acute Leukemia Mouse Model

Laure B. Bindels, Raphaël Beck, Olivier Schakman et al. · PLoS ONE · 2012 · 270 citations · Full text

Dysbiosis, Host-microbe Interactions, Immunology +18

Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells

Christophe J. De Saedeleer, Tamara Copetti, Paolo E. Porporato et al. · PLoS ONE · 2012 · 250 citations · Full text

Cancer Metabolism, Biochemistry, Oncogenic Agent +14