Concepedia

Dean Clarke

DC

6

Publications

1K

Citations

6

H-Index

2002

Active since

Affiliations

University of Leeds(Current)

Institute of Structural and Molecular Biology

University of Oxford

Dean Clarke is an author at University of Leeds specializing in microbiology, molecular biology, and synthetic biology.

Top concepts

Publications per year

2002–2015

6

Publications

6

The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, Amantadine

Stephen Griffin, Lucy Beales, Dean Clarke et al. · FEBS Letters · 2002 · 484 citations

A conserved basic loop in hepatitis C virus p7 protein is required for amantadine-sensitive ion channel activity in mammalian cells but is dispensable for localization to mitochondria

Stephen Griffin, Ruth Harvey, Dean Clarke et al. · Journal of General Virology · 2004 · 163 citations

Evidence for the Formation of a Heptameric Ion Channel Complex by the Hepatitis C Virus P7 Protein in Vitro

Dean Clarke, Stephen Griffin, Lucy Beales et al. · Journal of Biological Chemistry · 2006 · 132 citations · Full text

Tandem Fusion of Hepatitis B Core Antigen Allows Assembly of Virus-Like Particles in Bacteria and Plants with Enhanced Capacity to Accommodate Foreign Proteins

Hadrien Peyret, Gehin Annick, Eva C. Thuenemann et al. · PLoS ONE · 2015 · 119 citations · Full text

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Signal Peptide Cleavage and Internal Targeting Signals Direct the Hepatitis C Virus p7 Protein to Distinct Intracellular Membranes

Stephen Griffin, Dean Clarke, Christopher J. McCormick et al. · Journal of Virology · 2005 · 73 citations · Full text

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