Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs

Susannah L. Hewitt, Ailin Bai, D. R. Shackleton Bailey, +17

Science Translational Medicine

Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment

Susannah L. Hewitt, D. R. Shackleton Bailey, John Zielinski, +29

Clinical Cancer Research

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

Susannah L. Hewitt, Bu Yin, Yanhong Ji, +13

Nature Immunology

ImmunogeneticsAutoimmune DiseaseImmunodeficienciesGeneticsImmunology +8

Nuclear repositioning marks the selective exclusion of lineage‐inappropriate transcription factor loci during T helper cell differentiation

Susannah L. Hewitt, Frances A. High, Steven L. Reiner, +2

European Journal of Immunology

GeneticsSelective ExclusionEpigeneticsTranscriptional RegulationCpg Methylation +14

Association between the Igk and Igh immunoglobulin loci mediated by the 3′ Igk enhancer induces 'decontraction' of the Igh locus in pre–B cells

Susannah L. Hewitt, Deborah Farmer, Katarzyna Marszalek, +5

Nature Immunology

ImmunogeneticsIgk Enhancer InducesPre–b CellsLymphocyte DevelopmentGenetics +9

B-1a cells acquire their unique characteristics by bypassing the pre-BCR selection stage

Jason Wong, Susannah L. Hewitt, Lynn Heltemes-Harris, +7

Nature Communications

A Multifunctional Element in the Mouse <i>Igκ</i> Locus That Specifies Repertoire and <i>Ig</i> Loci Subnuclear Location

Yougui Xiang, Xiaorong Zhou, Susannah L. Hewitt, +2

The Journal of Immunology

Multifunctional ElementLymphocyte DevelopmentGeneticsViral ImmunityImmunology +22

Close Proximity to Igh Is a Contributing Factor to AID-Mediated Translocations

Pedro P. Rocha, Mariann Micsinai, Jung‐Hyun Kim, +7

Molecular Cell

Developmental BiologySignal TransductionGeneticsContributing FactorAid-mediated Translocations +4

RUNX Transcription Factor-Mediated Association of Cd4 and Cd8 Enables Coordinate Gene Regulation

Amélie Collins, Susannah L. Hewitt, Julie Chaumeil, +13

Immunity

Transcriptional RegulationMolecular RegulationGeneticsGene ExpressionGene Regulation +6

V _H replacement in primary immunoglobulin repertoire diversification

Amy Sun, Tatiana I. Novobrantseva, Maryaline Coffre, +5

Proceedings of the National Academy of Sciences