Formation of Dynamic γ-H2AX Domains along Broken DNA Strands Is Distinctly Regulated by ATM and MDC1 and Dependent upon H2AX Densities in Chromatin

Velibor Savic, Bu Yin, Nancy L. Maas, +6

Molecular Cell

ChromatinTranscriptional RegulationChromosome DynamicsChromatin StructureChromatin Remodeling +11

RAG-1 and ATM coordinate monoallelic recombination and nuclear positioning of immunoglobulin loci

Susannah L. Hewitt, Bu Yin, Yanhong Ji, +13

Nature Immunology

ImmunogeneticsAutoimmune DiseaseImmunodeficienciesGeneticsImmunology +8

ATR and H2AX Cooperate in Maintaining Genome Stability under Replication Stress

Rebecca A. Chanoux, Bu Yin, Karen Urtishak, +3

Journal of Biological Chemistry

Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice

Xiaohe Liu, Jodi L. Karnell, Bu Yin, +8

Journal of Clinical Investigation

Lymphocyte DevelopmentC-myc ExpressionT-regulatory CellImmune RegulationImmunology +17

Ataxia telangiectasia mutated (Atm) and DNA-PKcs kinases have overlapping activities during chromosomal signal joint formation

Eric J. Gapud, Yair Dorsett, Bu Yin, +10

Proceedings of the National Academy of Sciences

GeneticsGenomic MechanismMolecular BiologyCell DeathDsb Repair +17

Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination

Bu Yin, Velibor Savic, Marisa M. Juntilla, +6

The Journal of Experimental Medicine

Mice Heterozygous for Germ-line Mutations in Methylthioadenosine Phosphorylase ( <i>MTAP</i> ) Die Prematurely of T-Cell Lymphoma

Yuwaraj Kadariya, Bu Yin, Baiqing Tang, +8

Cancer Research

Tp53 deletion in B lineage cells predisposes mice to lymphomas with oncogenic translocations

Marta Rowh, Amy DeMicco, Julie Horowitz, +6

Oncogene

Lymphoid NeoplasiaTp53 DeletionOncogenic AgentMedicineOncogenic Translocations +6

ATM deficiency augments constitutively nuclear cyclin D1-driven genomic instability and lymphomagenesis

Laura Pontano Vaites, Zhaorui Lian, Eung‐Ryoung Lee, +4

Oncogene

ChromatinGenome InstabilityGenetic DisorderGeneticsPathology +4

Redundant and Nonredundant Functions of ATM and H2AX in αβ T-Lineage Lymphocytes

Bu Yin, Baeck-Seung Lee, Katherine Yang‐Iott, +2

The Journal of Immunology