Dayenne G. van Leeuwen

Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo

Sarwish Rafiq, Oladapo Yeku, Hollie J. Jackson et al. · Nature Biotechnology · 2018 · 823 citations

Medicine, Immunology, Oncology +16

Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System

Mauro P. Avanzi, Oladapo Yeku, Xinghuo Li et al. · Cell Reports · 2018 · 331 citations · Full text

Medicine, Immunology, Oncology +17

CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response

Nicholas F. Kuhn, Terence J. Purdon, Dayenne G. van Leeuwen et al. · Cancer Cell · 2019 · 238 citations · Full text

Life Sciences, Immunology, Oncology +12

Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression

Kevin J. Curran, Beatrijs A. Seinstra, Yan Nikhamin et al. · Molecular Therapy · 2015 · 215 citations · Full text

Life Sciences, Immunology, Oncology +17

IL-12-secreting CD19-targeted cord blood-derived T cells for the immunotherapy of B-cell acute lymphoblastic leukemia

Hollie J. Pegram, Terence J. Purdon, Dayenne G. van Leeuwen et al. · Leukemia · 2014 · 151 citations · Full text

Life Sciences, Immunology, Oncology +12