H Kozutsumi

Relationship between sugar chain structure and biological activity of recombinant human erythropoietin produced in Chinese hamster ovary cells.

Makoto Takeuchi, Noboru Inoue, T W Strickland et al. · Proceedings of the National Academy of Sciences · 1989 · 274 citations · Full text

Biological Activity, Standard Epo, Xenotransplantation +11

The C-terminal SH3 domain of the mouse c-Crk protein negatively regulates tyrosine-phosphorylation of Crk associated p130 in rat 3Y1 cells.

Seishi Ogawa, H. Toyoshima, H Kozutsumi et al. · PubMed · 1994 · 41 citations

An Epidermal Growth Factor Receptor-Leukocyte Tyrosine Kinase Chimeric Receptor Generates Ligand-dependent Growth Signals through the Ras Signaling Pathway

Hiroo Ueno, Naoto Hirano, H Kozutsumi et al. · Journal of Biological Chemistry · 1995 · 38 citations · Full text

Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein.

H. Toyoshima, H Kozutsumi, Yoshiro Maru et al. · Proceedings of the National Academy of Sciences · 1993 · 28 citations · Full text

Molecular Immunology, Signal Transduction, Signaling Pathway +13

Chemical modification of erythropoietin: an increase in in vitro activity by guanidination

Rika Satake, H Kozutsumi, Makoto Takeuchi et al. · Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology · 1990 · 27 citations

Biochemistry, Medicine, Physiology +6