Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas

Yasuo Horie, Akira Suzuki, Ei Kataoka, +12

Journal of Clinical Investigation

Nfil3/E4bp4 is required for the development and maturation of NK cells in vivo

Shintaro Kamizono, Gordon S. Duncan, Markus G. Seidel, +9

The Journal of Experimental Medicine

iRhom2 Regulation of TACE Controls TNF-Mediated Protection Against <i>Listeria</i> and Responses to LPS

David R. McIlwain, Philipp A. Lang, Thorsten Maretzky, +15

Science

The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis

Koichi Hamada, Takehiko Sasaki, Pandelakis A. Koni, +14

Genes & Development

Inhibition of angiogenesis and vascular leakiness by angiopoietin-related protein 4.

Yasuhiro Ito, Yuichi Oike, Kunio Yasunaga, +7

PubMed

InflammationMiles Permeability AssaysAngiogenesisVascular LeakinessMedicine +11

Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development

Takeshi Ueda, Masato Sasaki, Andrew Elia, +4

Proceedings of the National Academy of Sciences

Keratinocyte-specific Pten deficiency results in epidermal hyperplasia, accelerated hair follicle morphogenesis and tumor formation.

Akira Suzuki, Satoshi Itami, Minako Ohishi, +9

PubMed

Hair Follicle MorphogenesisPten DownstreamCell DeathDermatologyTumor Biology +17

Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11

Masato Sasaki, Kohichi Kawahara, Miki Nishio, +20

Nature Medicine

Mdm2-p53 PathwayTumor BiologyCell RegulationNucleolar Rpl11Medicine +6

Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice

Shigehisa Yanagi, Hiroyuki Kishimoto, Kohichi Kawahara, +12

Journal of Clinical Investigation

VEGF-C signaling pathways through VEGFR-2 and VEGFR-3 in vasculoangiogenesis and hematopoiesis

Koichi Hamada, Yuichi Oike, Nobuyuki Takakura, +5

Blood