David J. Maloney

High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell–like diffuse large B-cell lymphoma cells

Lesley A. Mathews Griner, Rajarshi Guha, Paul Shinn et al. · Proceedings of the National Academy of Sciences · 2014 · 390 citations · Full text

Gene expression analysis identifies global gene dosage sensitivity in cancer

Rudolf S.N. Fehrmann, Juha Karjalainen, Małgorzata Krajewska et al. · Nature Genetics · 2015 · 361 citations · Full text

Functional Genomics, Medicine, Cancer Genomics +7

Cooperative Epigenetic Modulation by Cancer Amplicon Genes

Lixin Rui, N. C. Tolga Emre, Michael J. Kruhlak et al. · Cancer Cell · 2010 · 276 citations · Full text

Chromatin, Medicine, Genetics +9

A selective USP1–UAF1 inhibitor links deubiquitination to DNA damage responses

Liang Qin, Thomas S. Dexheimer, Ping Zhang et al. · Nature Chemical Biology · 2014 · 265 citations · Full text

Genome Instability, Genomic Mechanism, Molecular Biology +2

KDM5 Histone Demethylase Activity Links Cellular Transcriptomic Heterogeneity to Therapeutic Resistance

Kunihiko Hinohara, Hua‐Jun Wu, Sébastien Vigneau et al. · Cancer Cell · 2018 · 248 citations · Full text

Histone Modifications, Chromatin, Chromatin Remodeling +9