Ivan Lieberburg

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.1K citations

Neurodegenerative Diseases, Alzheimer's Disease, Immunology +7

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

Alzheimer-type Neuropathology, Neurodegenerative Diseases, Alzheimer's Disease +12

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations · Full text

Amyloid β-Peptide Enter, Neurodegenerative Diseases, Alzheimer's Disease +13

Amyloid β-peptide is produced by cultured cells during normal metabolism

Christian Haass, Michael G. Schlossmacher, Albert Y. Hung et al. · Nature · 1992 · 1.9K citations

Amyloid β-Peptide, Protein Expression, Biochemistry +11

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

Neurodegenerative Diseases, Alzheimer's Disease, β-Amyloid Precursor Protein +10