Panagiotis A. Konstantinopoulos

Replication fork stability confers chemoresistance in BRCA-deficient cells

Arnab Ray Chaudhuri, Elsa Callén, Xia Ding et al. · Nature · 2016 · 904 citations · Full text

Brca-deficient Cells, Genome Instability, Natural Sciences +5

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Raphaël Ceccaldi, Ravindra Amunugama, Ildikó Hajdú et al. · Nature · 2015 · 859 citations · Full text

Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

Brooke E. Howitt, Sachet A. Shukla, Lynette M. Sholl et al. · JAMA Oncology · 2015 · 666 citations · Full text

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

Kyle C. Strickland, Brooke E. Howitt, Sachet A. Shukla et al. · Oncotarget · 2016 · 612 citations · Full text

Neoantigen Load, Brca1/2-mutation Status, Cancer Immunosurveillance +15

Single-Arm Phases 1 and 2 Trial of Niraparib in Combination With Pembrolizumab in Patients With Recurrent Platinum-Resistant Ovarian Carcinoma

Panagiotis A. Konstantinopoulos, Steven Waggoner, Gregory A. Vidal et al. · JAMA Oncology · 2019 · 533 citations · Full text