Panagiotis A. Konstantinopoulos

Replication fork stability confers chemoresistance in BRCA-deficient cells

Arnab Ray Chaudhuri, Elsa Callén, Xia Ding et al. · Nature · 2016 · 932 citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +14

Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair

Raphaël Ceccaldi, Ravindra Amunugama, Ildikó Hajdú et al. · Nature · 2015 · 888 citations · Full text

Medicine, Cancer Biology, Oncology +14

Association of Polymerase e–Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1

Brooke E. Howitt, Sachet A. Shukla, Lynette M. Sholl et al. · JAMA Oncology · 2015 · 685 citations · Full text

Medicine, Immunology, Oncology +17

Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer

Kyle C. Strickland, Brooke E. Howitt, Sachet A. Shukla et al. · Oncotarget · 2016 · 621 citations · Full text

Life Sciences, Immunology, Oncology +17

PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer

Liya Ding, Hye‐Jung Kim, Qiwei Wang et al. · Cell Reports · 2018 · 571 citations · Full text

Medicine, Oncology, Pharmacology +17