Repurposing the CRISPR-Cas9 system for targeted DNA methylation

Aleksandar Vojta, Paula Dobrinić, Vanja Tadić, +5

Nucleic Acids Research

Integrative epigenome-wide analysis demonstrates that DNA methylation may mediate genetic risk in inflammatory bowel disease

Nicholas T. Ventham, Nicholas A. Kennedy, Alex Adams, +103

Nature Communications

Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells

James Rhodes, Angelika Feldmann, Benjamín Hernández-Rodríguez, +13

Cell Reports

ChromatinDevelopmental BiologyChromatin StructureMedicineStem Cell Research +7

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

Lucija Klarić, Yakov A. Tsepilov, Chloë M. Stanton, +50

Science Advances

PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency

Paula Dobrinić, Aleksander Szczurek, Robert J. Klose

Nature Structural & Molecular Biology

ChromatinTranscriptional RegulationPolycomb-mediated Gene RepressionCell RegulationMedicine +9

BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome

Nadezda A. Fursova, Anne H. Turberfield, Neil P. Blackledge, +5

Genes & Development

Cross-phosphorylation of bacterial serine/threonine and tyrosine protein kinases on key regulatory residues

Lei Shi, Nathalie Pigeonneau, Vaishnavi Ravikumar, +5

Frontiers in Microbiology

BacteriologyMolecular BiologyBacterial Serine/threonineProteomicsTyrosine Protein +14

Promoter methylation of the MGAT3 and BACH2 genes correlates with the composition of the immunoglobulin G glycome in inflammatory bowel disease

Marija Klasić, Dora Markulin, Aleksandar Vojta, +17

Clinical Epigenetics

PRC1 drives Polycomb-mediated gene repression by controlling transcription initiation and burst frequency

Paula Dobrinić, Aleksander Szczurek, Robert J. Klose

Polycomb-mediated Gene RepressionPolycomb Chromatin DomainsGeneticsCell PopulationGene Regulatory Network +20

Genome-Wide Methylation Profiling in 229 Patients With Crohn’s Disease Requiring Intestinal Resection: Epigenetic Analysis of the Trial of Prevention of Post-operative Crohn’s Disease (TOPPIC)

Nicholas T. Ventham, Nicholas A. Kennedy, Rahul Kalla, +101

Cellular and Molecular Gastroenterology and Hepatology