Karen Dodge

TTI-621 (SIRPαFc): A CD47-Blocking Innate Immune Checkpoint Inhibitor with Broad Antitumor Activity and Minimal Erythrocyte Binding

Penka S. Petrova, Natasja Nielsen Viller, Mark Wong et al. · Clinical Cancer Research · 2016 · 269 citations

Peroxynitrite impairs cardiac contractile function by decreasing cardiac efficiency

Richard Schulz, Karen Dodge, Gary D. Lopaschuk et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1997 · 102 citations

Cardiac Muscle, Heart Failure, Medicine +12

TTI-621 (SIRPαFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets

Gloria H. Y. Lin, Vien Chai, Vivian Lee et al. · PLoS ONE · 2017 · 59 citations · Full text

Tumor-associated Macrophages, Immune Regulation, Immunology +24

Pyruvate Augments Mechanical Function via Activation of the Pyruvate Dehydrogenase Complex in Reperfused Ischemic Immature Rabbit Hearts

Yoshikatsu Saiki, Gary D. Lopaschuk, Karen Dodge et al. · Journal of Surgical Research · 1998 · 21 citations

Mechanobiology, Cardiac Muscle, Cardiomyopathy +10

Abstract 2709: TTI-622 (SIRPα-IgG4 Fc), a CD47-blocking innate immune checkpoint inhibitor, suppresses tumor growth and demonstrates enhanced efficacy in combination with antitumor antibodies in both hematologic and solid tumor models

Gloria H. Y. Lin, Natasja Nielsen Viller, Marilyse Chabonneau et al. · Cancer Research · 2018 · 12 citations

Immunology, Immune Regulation, Cell Death +22