Hui-Li Ng

Design, Synthesis, and Biological Evaluation of Coupled Bioactive Scaffolds as Potential Anticancer Agents for Dual Targeting of Dihydrofolate Reductase and Thioredoxin Reductase

Hui-Li Ng, Xiang Ma, Eng‐Hui Chew et al. · Journal of Medicinal Chemistry · 2017 · 63 citations · Full text

Cellular Dhfr, Dhfr Inhibition, Chemical Biology +16

Sulforaphane and its methylcarbonyl analogs inhibit the LPS-stimulated inflammatory response in human monocytes through modulating cytokine production, suppressing chemotactic migration and phagocytosis in a NF-κB- and MAPK-dependent manner

Shridhivya A. Reddy, Sandeep B. Shelar, Truong‐Minh Dang et al. · International Immunopharmacology · 2015 · 34 citations

Microbial Pathogens, Immune Regulation, Immunology +16

Applying the designed multiple ligands approach to inhibit dihydrofolate reductase and thioredoxin reductase for anti-proliferative activity

Hui-Li Ng, Shangying Chen, Eng‐Hui Chew et al. · European Journal of Medicinal Chemistry · 2016 · 33 citations · Full text

Aldo-keto Reductase, Aldehyde Dehydrogenase, Biochemistry +8

Novel dual-targeting anti-proliferative dihydrotriazine-chalcone derivatives display suppression of cancer cell invasion and inflammation by inhibiting the NF-κB signaling pathway

Fei-Fei Gan, Ruirui Zhang, Hui-Li Ng et al. · Food and Chemical Toxicology · 2018 · 29 citations

Medicinal Chemistry, Medicine, Immunology +11