Derek J. Cashman

Biophysical Studies of the c-MYC NHE III1 Promoter: Model Quadruplex Interactions with a Cationic Porphyrin

Matthew W. Freyer, Robert Buscaglia, Kimberly Kaplan et al. · Biophysical Journal · 2006 · 140 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

A New Bisintercalating Anthracycline with Picomolar DNA Binding Affinity

José Portugal, Derek J. Cashman, John O. Trent et al. · Journal of Medicinal Chemistry · 2005 · 58 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +17

A Computational Model for Anthracycline Binding to DNA:  Tuning Groove-Binding Intercalators for Specific Sequences

Derek J. Cashman, Glen E. Kellogg · Journal of Medicinal Chemistry · 2004 · 49 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Binding of netropsin to several DNA constructs: Evidence for at least two different 1:1 complexes formed from an –AATT-containing ds-DNA construct and a single minor groove binding ligand

Matthew W. Freyer, Robert Buscaglia, Derek J. Cashman et al. · Biophysical Chemistry · 2006 · 43 citations

Life Sciences, Biology, Molecular Biology +11

Biophysical Characterization of an Ensemble of Intramolecular i-Motifs Formed by the Human c-MYC NHE III1 P1 Promoter Mutant Sequence

Jamie M. Dettler, Robert Buscaglia, Jingjing Cui et al. · Biophysical Journal · 2010 · 43 citations · Full text

Life Sciences, Genetics, Molecular Biology +13