Sns and Kirre, the <i>Drosophila</i> orthologs of Nephrin and Neph1,direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes

Shufei Zhuang, Huanjie Shao, Fengli Guo, +3

Development

Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer

Huanjie Shao, Esraa Mohamed, Guoyan Xu, +7

Oncotarget

Apigenin Sensitizes Colon Cancer Cells to Antitumor Activity of ABT-263

Huanjie Shao, Kai Jing, Esraa Mahmoud, +3

Molecular Cancer Therapeutics

Tumor BiologyAntitumor ActivityChemoprevention StrategyOncogenic AgentApigenin Treatment +13

AIM2 promotes the development of non-small cell lung cancer by modulating mitochondrial dynamics

Qi Miao, Dan Dai, Jin Liu, +11

Oncogene

Tumor BiologyMitochondrial BiogenesisMitochondrial FunctionMitochondrial DynamicMedicine +6

Mcl-1 downregulation by YM155 contributes to its synergistic anti-tumor activities with ABT-263

Haikuo Tang, Huanjie Shao, Chunrong Yu, +1

Biochemical Pharmacology

Mcl-1 DownregulationMedicineOncogenic AgentSynergistic Anti-tumor ActivitiesYm155 Contributes +8

Dihydroartemisinin suppresses STAT3 signaling and Mcl-1 and Survivin expression to potentiate ABT-263-induced apoptosis in Non-small Cell Lung Cancer cells harboring EGFR or RAS mutation

Xiaohui Yan, Pengfei Li, Yihong Zhan, +8

Biochemical Pharmacology

Tumor BiologyAbt-263-induced ApoptosisMedicinePharmacologyCell Death +7

Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells

Abir Mukherjee, Yibao Ma, Fang Yuan, +6

Neoplasia

Abstract 1: Mcl-1 downregulation plays a crucial role in the synergistic anticancer activities between PI-3 kinase inhibitors and histone deacetylase inhibitors in primary NSCLC tumors <i>in vitro</i> and <i>in vivo</i>

Hao Zhang, Haikou Tang, Huanjie Shao, +7

Cancer Research

ApoptosisCell DeathCancer BiologyTumor BiologyMolecular Pharmacology +17

Dual targeting of mTORC1/C2 complexes enhances histone deacetylase inhibitor-mediated anti-tumor efficacy in primary HCC cancer in vitro and in vivo

Huanjie Shao, Chun Gao, Haikuo Tang, +8

Journal of Hepatology

OncologyMtorc1/c2 ComplexesMedicinePrimary Hcc CancerPharmacology +7

Dock mediates Scar- and WASp-dependent actin polymerization through interaction with cell adhesion molecules in founder cells and fusion-competent myoblasts

Balasankara Reddy Kaipa, Huanjie Shao, Gritt Schäfer, +7

Journal of Cell Science

Founder CellsCell AdhesionCytoskeletonWasp-dependent Actin PolymerizationBiomedical Engineering +17