Ioannis N. Melas

Identifying Drug Effects via Pathway Alterations using an Integer Linear Programming Optimization Formulation on Phosphoproteomic Data

Alexander Mitsos, Ioannis N. Melas, Paraskeuas Siminelakis et al. · PLoS Computational Biology · 2009 · 139 citations · Full text

Rheumatoid arthritis patients display B-cell dysregulation already in the naïve repertoire consistent with defects in B-cell tolerance

Yan Wang, Katy A. Lloyd, Ioannis N. Melas et al. · Scientific Reports · 2019 · 74 citations · Full text

The species translation challenge—A systems biology perspective on human and rat bronchial epithelial cells

Carine Poussin, Carole Mathis, Leonidas G. Alexopoulos et al. · Scientific Data · 2014 · 56 citations · Full text

Engineering, Lung Inflammation, Immunology +22

Identification of drug-specific pathways based on gene expression data: application to drug induced lung injury

Ioannis N. Melas, Theodore Sakellaropoulos, Francesco Iorio et al. · Integrative Biology · 2015 · 48 citations · Full text

Detecting and Removing Inconsistencies between Experimental Data and Signaling Network Topologies Using Integer Linear Programming on Interaction Graphs

Ioannis N. Melas, Regina Samaga, Leonidas G. Alexopoulos et al. · PLoS Computational Biology · 2013 · 44 citations · Full text

Engineering, Machine Learning, Cross-referencing Experimental Data +21