Christian P. Kratz

Comprehensive Analysis of Hypermutation in Human Cancer

Brittany Campbell, Nicholas Light, David Fabrizio et al. · Cell · 2017 · 772 citations · Full text

Somatic Variant, Cancer Genomics, Comprehensive Analysis +5

Germline KRAS mutations cause Noonan syndrome

Suzanne Schubbert, Martin Zenker, Sara L. Rowe et al. · Nature Genetics · 2006 · 736 citations

Germline Kras Mutations, Mendelian Disorder, Genetic Disorder +6

Detectable clonal mosaicism and its relationship to aging and cancer

Kevin B. Jacobs, Meredith Yeager, Weiyin Zhou et al. · Nature Genetics · 2012 · 585 citations · Full text

Cell Division, Tumor Heterogeneity, Detectable Clonal Mosaicism +10

BRAF gene duplication constitutes a mechanism of MAPK pathway activation in low-grade astrocytomas

Stefan M. Pfister, Wibke G. Janzarik, Marc Remke et al. · Journal of Clinical Investigation · 2008 · 511 citations · Full text

Genetics, Pathology, Mapk Pathway Activation +20

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort

Sebastian M. Waszak, Paul A. Northcott, Ivo Buchhalter et al. · The Lancet Oncology · 2018 · 383 citations · Full text