Florent Laferrière

Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation

Tariq Afroz, Eva‐Maria Hock, Patrick Erñst et al. · Nature Communications · 2017 · 326 citations · Full text

TDP-43 extracted from frontotemporal lobar degeneration subject brains displays distinct aggregate assemblies and neurotoxic effects reflecting disease progression rates

Florent Laferrière, Zuzanna Maniecka, Manuela Pérez‐Berlanga et al. · Nature Neuroscience · 2018 · 198 citations · Full text

Aggregate Assemblies, Disease Progression Rates, Neurotoxic Effects +9

Novel self-replicating α-synuclein polymorphs that escape ThT monitoring can spontaneously emerge and acutely spread in neurons

Francesca De Giorgi, Florent Laferrière, Federica Zinghirino et al. · Science Advances · 2020 · 78 citations · Full text

Quaternary Structure of Pathological Prion Protein as a Determining Factor of Strain-Specific Prion Replication Dynamics

Florent Laferrière, Philippe Tixador, Mohammed Moudjou et al. · PLoS Pathogens · 2013 · 61 citations · Full text

Protein Assembly, Molecular Biology, Protein Phase Separation +18

Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function

Eva‐Maria Hock, Zuzanna Maniecka, Marián Hruška-Plocháň et al. · Cell Reports · 2018 · 60 citations · Full text