José-Ignacio Andrés

Author

José-Ignacio Andrés

Janssen (Belgium)

Also Known As

Jose-Ignacio Andrés, José-Ignacio Andrés

Publications

427

Citations

H-Index

Concepts

All Affiliations

Janssen (Belgium)KU Leuven Janssen (United States)Springhouse

About

José-Ignacio Andrés is an author at Janssen (Belgium) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	5	5	229
2	Natural Sciences	4	4	178
3	Biochemistry	4	4	178
4	Social Sciences	1	1	51
5	Molecular Biology	1	1	40

José-Ignacio Andrés

Publications

425

Citations

H-Index

Page 1

	Year	Citations
Preclinical Evaluation of a P2X7 Receptor–Selective Radiotracer: PET Studies in a Rat Model with Local Overexpression of the Human P2X7 Receptor and in Nonhuman Primates Dieter Ory, Sofie Celen, Rik Gijsbers, Journal of Nuclear Medicine	2016	87
Pyrido[4,3-<i>e</i>][1,2,4]triazolo[4,3-<i>a</i>]pyrazines as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors Frederik Rombouts, Gary Tresadern, Peter Buijnsters, ACS Medicinal Chemistry Letters Molecular PharmacologyMedicinal ChemistryPharmaceutical ScienceProtein FlexibilityBiochemistry	2015	56
Synthesis, Evaluation, and Radiolabeling of New Potent Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 2 as Potential Tracers for Positron Emission Tomography Imaging José-Ignacio Andrés, Jesús Alcázar, José M. Cid, Journal of Medicinal Chemistry Allosteric Binding SitePeptide ScienceNew SeriesPre-clinical PharmacologyTranslational Pharmacology	2012	53
Structure-Based Design of a Potent, Selective, and Brain Penetrating PDE2 Inhibitor with Demonstrated Target Engagement Peter Buijnsters, Meri De Angelis, Xavier Langlois, ACS Medicinal Chemistry Letters Drug TargetNeurochemical BiomarkersClinical NeuroscienceSocial SciencesMolecular Pharmacology	2014	51
Synthesis, In Vivo Occupancy, and Radiolabeling of Potent Phosphodiesterase Subtype-10 Inhibitors as Candidates for Positron Emission Tomography Imaging José-Ignacio Andrés, Meri De Angelis, Jesús Alcázar, Journal of Medicinal Chemistry	2011	43
Discovery of <i>N</i>-(Pyridin-4-yl)-1,5-naphthyridin-2-amines as Potential Tau Pathology PET Tracers for Alzheimer’s Disease Frederik Rombouts, José-Ignacio Andrés, Manuela Ariza, Journal of Medicinal Chemistry Pharmaceutical ScienceModest Selectivity VersusMolecular BiologyNeurochemical BiomarkersPeptide Science	2017	40
What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of <sup>11</sup>C-JNJ-42491293, A Novel Radioligand for mGluR2 Gil Leurquin‐Sterk, Sofie Celen, Koen Van Laere, Journal of Nuclear Medicine	2016	33
Discovery of <i>N</i>-(4-[<sup>18</sup>F]Fluoro-5-methylpyridin-2-yl)isoquinolin-6-amine (JNJ-64326067), a New Promising Tau Positron Emission Tomography Imaging Tracer Frederik Rombouts, Lieven Declercq, José-Ignacio Andrés, Journal of Medicinal Chemistry	2019	33
Discovery of a new series of [1,2,4]triazolo[4,3-a]quinoxalines as dual phosphodiesterase 2/phosphodiesterase 10 (PDE2/PDE10) inhibitors José-Ignacio Andrés, Peter Buijnsters, Meri De Angelis, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryMedicinal ChemistryBiochemistryAntiparasitic AgentMedicine	2012	29

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